Learn · Testosterone

Testosterone enanthate: doses, forms, storage and cost

By Open Water Rx Editorial Team. Published November 6, 2026. Sources checked November 6, 2026.

Short answer

Testosterone enanthate is a long-acting form of testosterone given by injection. It comes in two FDA-approved forms: a 200 mg/ml multi-dose vial injected into the muscle, and Xyosted, a single-dose autoinjector given under the skin of the abdomen once a week in 50, 75 or 100 mg strengths. Testosterone is a Schedule III controlled substance, and treatment starts only after morning blood tests on at least two separate days confirm low testosterone. Your prescriber sets your dose.

The two forms

Testosterone enanthate in its two FDA-approved forms side by side: the 200 mg/ml vial and the Xyosted autoinjector, with strength, injection site, label dosing, oil and storage.
DetailTestosterone enanthate vialXyosted autoinjector
Strength200 mg/ml, 5 ml multi-dose vial50, 75 or 100 mg in 0.5 ml
Where it is injectedDeep in the gluteal muscleUnder the skin of the abdomen
Label dosing50 to 400 mg every 2 to 4 weeks; total doses above 400 mg a month are generally not requiredStart at 75 mg once a week; adjust based on a trough level 7 days after a dose, after 6 weeks
OilSesame oilPreservative-free solution
StorageRoom temperature, 20 to 25°C (68 to 77°F); warm and roll the vial if crystals form in the coldRoom temperature; do not refrigerate or freeze; protect from light

Before you start

The labels say to confirm low testosterone with morning blood tests on at least two separate days before starting.

Monitoring the labels describe

  • Hematocrit about every 3 months (Xyosted label), because testosterone can raise red blood cell levels.

  • Blood pressure, which testosterone can raise.

  • Prostate symptoms in men with an enlarged prostate.

  • Signs of blood clots in the legs or lungs.

These are the checks the labels describe. They are not a schedule you can set for yourself, and no dose on this page is a recommendation.

What it costs online

This guide records what each program charges on its own page, with the date the figure was read. The 9 programs that publish a monthly figure charge from $28 to $250 a month on known charges, with a median of $149. The lowest verified all-in figure is $199 a month. Those records were read between October 23 and October 26, 2026, and each one carries its own check date. See how much does testosterone therapy cost. Then see Xyosted and Injectable vs topical TRT cost.

Surfbound Health · Operated by the publisher of this guide

Surfbound Health sells compounded sermorelin after a licensed provider review: injectable at $169 a month (low dose) or $249 a month (high dose) on a one-month plan, and oral (sublingual) from $149 a month, with no membership fee. Prepaid 3-month and 6-month bundles are also listed. Lab work is typically required. Compounded sermorelin is not FDA-approved. Surfbound Health does not sell testosterone therapy, is not a provider in this edition and takes no part in its ranking. Source: surfbound.co/sermorelin, read November 6, 2026.

Surfbound's sermorelin prices

Open Water RX LLC publishes this guide, GLP1BuyerGuide.com and HRTBuyerGuide.com, and operates Surfbound Health, a consumer telehealth brand.

Frequently asked questions

What is testosterone enanthate?

A long-acting form of testosterone given by injection, sold as a 200 mg/ml vial for intramuscular use and as the Xyosted autoinjector for weekly use under the skin.

How often is testosterone enanthate injected?

The vial label gives 50 to 400 mg every 2 to 4 weeks. Xyosted is given once a week. Your prescriber sets the schedule.

Does testosterone enanthate need to be refrigerated?

No. Both labels say to store it at room temperature. The Xyosted label says not to refrigerate or freeze it.

Is testosterone enanthate a controlled substance?

Yes. Testosterone is a Schedule III controlled substance in the United States.

Sources

Controlled substance

Testosterone is a Schedule III controlled substance in the United States. Prescribing rules, in-person examination requirements and refill limits vary by state and provider, and federal telehealth rules for controlled substances apply alongside state law. Nothing here claims a program can prescribe to you; this publication compares published prices and billing terms only.

This page summarizes published prescribing information and medical references on the dates shown. It is not medical advice and does not recommend a treatment.