Learn · Dosing

Is 1 ml of testosterone a week enough?

By Open Water Rx Editorial Team. Published November 6, 2026. Sources checked November 6, 2026.

Short answer

It depends on the vial. Testosterone cypionate comes in 100 mg/ml and 200 mg/ml strengths, and testosterone enanthate vials are 200 mg/ml, so 1 ml a week is either 100 mg or 200 mg a week. The Endocrine Society’s 2018 guideline lists typical starting regimens of 75 to 100 mg a week, or 150 to 200 mg every 2 weeks. So 1 ml of a 100 mg/ml vial is within the weekly range, and 1 ml of a 200 mg/ml vial is double the upper weekly figure. Whether any dose is enough is judged by blood tests and symptoms, and only your prescriber should change it.

What 1 ml contains

What a given volume of testosterone injection contains at a 100 mg/ml strength and at a 200 mg/ml strength, from 0.25 ml to 1 ml.
VolumeAt 100 mg/mlAt 200 mg/ml
0.25 ml (25 units on a U-100 syringe)25 mg50 mg
0.375 ml (37.5 units)37.5 mg75 mg
0.5 ml (50 units)50 mg100 mg
0.75 ml (75 units)75 mg150 mg
1 ml (100 units)100 mg200 mg

Read the strength printed on your vial. The same volume from a different vial can be a different dose.

What the references say

What the Depo-Testosterone label, the testosterone enanthate label and the 2018 Endocrine Society guideline say about dosing.
SourceWhat it says
Depo-Testosterone (testosterone cypionate) labelFor replacement in hypogonadal males, 50 to 400 mg every two to four weeks
Testosterone enanthate labelTotal doses above 400 mg a month are generally not required; injections more often than every two weeks are rarely indicated
Endocrine Society guideline (2018)Typical starting doses of enanthate or cypionate: 75 to 100 mg a week, or 150 to 200 mg every 2 weeks
Endocrine Society guideline (2018)Aim for testosterone levels in the mid-normal range during treatment

How "enough" is judged

  • Blood levels. Your prescriber checks testosterone during treatment and adjusts the dose to reach the target range. For the weekly autoinjector Xyosted, the label times the check 7 days after a dose, after 6 weeks of treatment.

  • Hematocrit. Testosterone can raise red blood cell levels; the Xyosted label advises checking hematocrit about every 3 months.

  • Symptoms and side effects, discussed with your prescriber.

These are the checks a prescriber uses. They are not a target you can set for yourself, and no dose on this page is a recommendation.

Weekly vs every two weeks

The Endocrine Society lists both a weekly schedule and an every-two-weeks schedule. Your prescriber chooses the schedule and checks levels at the right point between injections.

What it costs online

This guide records what each program charges on its own page, with the date the figure was read. The 9 programs that publish a monthly figure charge from $28 to $250 a month on known charges, with a median of $149. The lowest verified all-in figure is $199 a month. Those records were read between October 23 and October 26, 2026, and each one carries its own check date. See how much does testosterone therapy cost. Then see Injectable vs topical TRT cost.

Surfbound Health · Operated by the publisher of this guide

Surfbound Health sells compounded sermorelin after a licensed provider review: injectable at $169 a month (low dose) or $249 a month (high dose) on a one-month plan, and oral (sublingual) from $149 a month, with no membership fee. Prepaid 3-month and 6-month bundles are also listed. Lab work is typically required. Compounded sermorelin is not FDA-approved. Surfbound Health does not sell testosterone therapy, is not a provider in this edition and takes no part in its ranking. Source: surfbound.co/sermorelin, read November 6, 2026.

Surfbound's sermorelin prices

Open Water RX LLC publishes this guide, GLP1BuyerGuide.com and HRTBuyerGuide.com, and operates Surfbound Health, a consumer telehealth brand.

Frequently asked questions

Is 1 ml of testosterone a week enough?

1 ml is 100 mg or 200 mg depending on the vial strength. The Endocrine Society lists 75 to 100 mg a week as a typical starting regimen, so the answer depends on your vial, your blood levels and your prescriber.

How many mg is 1 ml of testosterone cypionate?

100 mg in a 100 mg/ml vial, or 200 mg in a 200 mg/ml vial.

How many units is 1 ml of testosterone?

1 ml is 100 units on a U-100 insulin syringe.

What is a normal weekly testosterone dose?

The Endocrine Society’s 2018 guideline lists typical starting doses of 75 to 100 mg a week, or 150 to 200 mg every 2 weeks, for enanthate or cypionate.

Can I change my own testosterone dose?

No. Dose changes should come from your prescriber, based on blood tests and symptoms.

Sources

Controlled substance

Testosterone is a Schedule III controlled substance in the United States. Prescribing rules, in-person examination requirements and refill limits vary by state and provider, and federal telehealth rules for controlled substances apply alongside state law. Nothing here claims a program can prescribe to you; this publication compares published prices and billing terms only.

This page summarizes published prescribing information and medical references on the dates shown. It is not medical advice and does not recommend a treatment.